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It can be removed predominantly by hepatic metabolism (largely CYP3A4) and is also transformed to an active metabolite with Qualities just like the dad or mum, sildenafil. Both sildenafil plus the metabolite have terminal 50 % life of about four hours.
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Extreme Allergic Reactions. Sildenafil may perhaps bring about allergic reactions, that may be significant. Prevent getting sildenafil and obtain help at once When you've got any of the following indicators of a significant allergic reaction.
Viagra together with other products and solutions for sexual dysfunction, termed sexuopharmaceuticals, proliferated new types of specialised promoting for such products.[seventy four] Viagra and very similar prescription prescribed drugs have been promoted by photos in media on the extent of getting to be a cultural icon, at some time a comparatively new phenomenon recognized to become permitted only in The us and New Zealand and that is believed to have significantly contributed to norms concerning male sexuality.
Merk: Beslutninger om behandling vurderes i fellesskap av forskriver og pasient less than konsultasjonen. Den endelige avgjørelsen vil imidlertid alltid være forskriverens.
Though much less frequent, by far the most major side effects of sildenafil are explained down below, coupled with how to proceed when they take place.
There isn't any managed medical information on the protection or efficacy of VIAGRA in people with retinitis pigmentosa (a minority kjøpe viagra i norge of such people have genetic Issues of retinal phosphodiesterases); if prescribed, this should be accomplished with caution.
Sildenafil is often a strong and selective inhibitor of cGMP-specific phosphodiesterase sort 5 (PDE5), that's chargeable for degradation of cGMP in the corpus cavernosum. The molecular structure of sildenafil is analogous to that of cGMP and acts like a competitive binding agent of PDE5 during the corpus cavernosum, leading to far more cGMP and elevated penile reaction to sexual stimulation.
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There won't be any managed clinical info on the safety or efficacy of VIAGRA in the following teams; if prescribed, this should be carried out with caution.
Doctors really should explore with clients the amplified risk of NAION in individuals who have already professional NAION in a single eye. Physicians also needs to talk about with patients the increased possibility of NAION among the overall populace in people having a “crowded” optic disc, although proof is insufficient to support screening of possible users of PDE5 inhibitor, like VIAGRA, for this unheard of condition [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS].
Det er viktig at du ikke kombinerer denne potenspillen med andre legemidler uten at du har opplyst legen om at du bruker disse medisinene.
Hvis de lavere dosene ikke har fungert for deg, og du ikke har hatt noen bivirkninger med de lavere dosene, vil du sannsynligvis bli foreskrevet Viagra 100mg. Det er den maksimale tilgjengelige dosen.